Neuroblastoma is the most common malignancy in children less than one year of age, but is rare in adults. Adult neuroblastoma differs from pediatric cases by lacking classical features including low incidence of MYCN amplification, elevated urinary catecholamimes, and MIBG avidity. The diagnosis may not be initially considered because of the. T1 - Neuroblastoma in adults. T2 - Diagnosis and treatment. AU - Cao, Yanna. AU - Yan, Jie. AU - Wang, Huijuan. PY - 2014/8/15. Y1 - 2014/8/15. N2 - Neuroblastoma (NB) is a common malignant solid tumor that occurs during childhood; it has a significant heterogeneity in clinical symptoms and outcome.Author: Yanna Cao, Jie Yan, Huijuan Wang.
PURPOSE: Clinical data on survival outcomes of adult patients (defined as 20 years of age and older) with neuroblastoma are scarce due to the rarity of the disease. Small single institution reports have described worse outcomes for adults than pediatric patients.Cited by: 103. Mar 19, 2018 · The types of cancers that develop in children are often different from the types that develop in adults. To learn more about, see What Are the Differences Between Cancers in Adults and Children? Neuroblastoma starts in certain very early forms of nerve cells, most often found in Last Revised: March 19, 2018.
Background. Staging and treatment of adult neuroblastoma has yet to be formalized. We sought to determine the utility of the pediatric classification system in adults and determine the efficacy of different treatment modalities. Methods. Medical records of 118 adults (patients >17 years old) and 112 pediatric patients (ages 2–17), who were treated for neuroblastoma at M.D. Anderson Cancer Cited by: 8.